An 84-year-old female was admitted to our hospital because of hematemesis and melena. At emergency gastrointestinal endoscopy, multiple diverticula with clot were visualized in the second portion of the duodenum. Since active bleeding from the diverticulum persisted, although a vessel was not visible, endoscopic hemostasis was performed using clipping. However, she developed massive melena 6 days after. Endoscopic examination revealed active bleeding from the diverticulum in the oral side of the papilla of Vater, and hemostasis using clipping was performed successfully. No hemorrhage occurred thereafter. The case in this study suggests that endoscopic clipping is a safe and effective method of hemostasis for the hemorrhage from the diverticulum.
