A case of cervical esophageal adenocarcinoma arising from ectopic gastric mucosa

Abstract

A pedunculated polyp was identified by gastrointestinal endoscopy in the cervical esophagus of a 60-year-old male. Esophageal adenocarcinoma was diagnosed by analysis of biopsy specimens. The depth of tumor invasion was thought to be within the mucosa and hence endoscopic mucosal resection was performed under general anesthesia, without complication. Histopathological examination revealed that the lesion was a moderately differentiated adenocarcinoma in situ (pT1a-LPM) arising from ectopic gastric mucosa. Lymphovascular invasion was negative and the margins were free from carcinoma. This case of cervical esophageal adenocarcinoma arising from ectopic gastric mucosa is rare, and to our knowledge only 19 cases─including this one─have been reported in Japan. Of these, endoscopic treatment was successful in just three cases. Careful endoscopic observation is required to discover this type of esophageal carcinoma.