Risk factors for rebleeding following endoscopic hemostasis in peptic ulcers

Abstract

Background and Aim : Although development of endoscopic procedures enables hemostasis to be achieved endoscopically, some cases still prove difficult for this procedure. Re-bleeding or even fatal cases have occurred. We retrospectively analyzed endoscopic hemostasis for hemorrhagic peptic ulcer bleeding in our department.
Subjects and Method : A total of 141 patients underwent endoscopic hemostasis for hemorrhagic gastroduodenal ulcer in our department between January 2008 and November 2012. These patients were divided into two groups : successful and re-bleeding. Multivariate analysis was used to examine various factors─patient background, endoscopy-related and surgeon-related─as risk factors for rebleeding.
Results : In the 141 cases, the average age was 67.2±16 and the male-to-female sex ratio was 104 : 37. In the successful group, average age was 66.5±16 and male-to-female ratio was 88 : 34. In the re-bleeding group, average age was 71.7±16, and male-to-female ratio was 16 : 3. In the re-bleeding group, there were significantly more patients with comorbidity, and patients who received transfusions. Multivariate analysis results suggest that comorbidity is a risk factor for rebleeding.
Conclusion : Patients with comorbidity may be at increased risk of re-bleeding. Strict observation of patients is necessary after endoscopic hemostasis procedures.