Abstract
A 64-year-old female was diagnosed with advanced type 3 gastric cancer with para-aortic lymph node metastases. Since a curative operation was deemed impossible, S-1/DOC combination therapy was administered. After five courses of chemotherapy, both the primary tumor and metastatic lesions reduced in size but a CT scan showed metastasis of Virchow’s lymph nodes. The patient therefore received 2nd line chemotherapy with CPT-11/CDDP. Repeated CT showed that Virchow’s lymph nodes further diminished in size. After 18 courses of treatment, however, the treatment had an adverse effect (renal dysfunction) . As 3rd line chemotherapy, CPT-11 alone was administered. After 13 courses of treatment, the primary lesion was remarkably improved and para-aortic lymph node metastases had disappeared. We discontinued chemotherapy after an additional 26 courses of treatment, followed by observation. The patient has now been in good health without a recurrence.
