Abstract
A 78-year-old man underwent total colonoscopy to investigate a positive fecal occult blood test, and was diagnosed with three submucosal tumors (SMTs) of the rectum. He was admitted to our department and endoscopic submucosal dissection (ESD) was performed on the largest lesion. Histological findings confirmed the diagnosis of mucosa-associated lymphoid tissue (MALT) lymphoma. Since MALT lymphoma is generally a low grade lymphoma, additional chemotherapy or surgery was not performed. Subsequently the other two lesions were treated by endoscopic mucosal resection (EMR) . Since the patient was also infected with H. pylori, eradication therapy was administered (and confirmed to be successful) . There has been no evidence of recurrence during the four years following treatment. Colorectal MALT lymphoma is a rare disease. Although H. pylori eradication is the treatment of choice for gastric MALT lymphoma, no standard therapy has been established for colorectal MALT lymphoma. Previously, surgical resection was most common performed, but recent reports even show efficacy of H. pylori eradication against colorectal MALT lymphoma. In this case, H. pylori eradication after ESD was effective and there have been no signs of recurrence in four years after treatment.
