抄録
Eosinophilic esophagitis (EoE) is rarely reported in Japan. We experienced two cases of EoE in one year.
Case 1 : A 55-year-old woman with an allergic rhinitis complained of heart burn. Endoscopy revealed that esophageal mucosa was so thick as to be unable to observe the vessels, and white exudates and longitudinal furrows were found in the esophagus. Its caliber was slightly narrow.
Case 2 : A 40-year-old man complained of nausea with no history of allergic disease. About one-third of the circumference in the middle esophagus, mucosal thickening and longitudinal furrows were observed during endoscopy, where the vessels were obscured. In both cases, histological examination of biopsy specimens revealed marked eosinophil infiltration in the esophageal mucosa, more than 20 per high-power field (HPF) .
These patients were diagnosed with EoE based on the diagnostic guideline, but their histories and endoscopic findings were considerably different. It will be necessary to elucidate what brought about the differences.
