Abstract
A 62-year-old man was referred to our hospital for additional examination of a duodenal tumor. Esophagogastroduodenoscopy revealed a 30 mm-sized submucosal tumor located immediately below the major vater of the second part of the duodenum. Endoscopic ultrasonography showed the heterogeneous echoic tumor was located in the submucosa. An abdominal CT scan did not delineate any metastatic lesions. Endoscopic polypectomy using a loop snare was performed without any complications. Histologically, the tumor was diagnosed as a gangliocytic paraganglioma. Clinically, a submucosal tumor may be recognized as a gangliocytic paraganglioma if the tumor is located near the ampullary region and is visualized as an heterogeneous tumor by endoscopic ultrasonography. As a gangliocytic paraganglioma is generally considered to be a benign tumor, the tumor should be resected using a less invasive method, such as endoscopic resection.