Eight cases of pyloric gland adenoma in the duodenum

Abstract

Pyloric gland adenoma is a rare tumor in which fundus glands differentiate into mucus neck cells at has a predilection for upper and middle body of the stomach but also occures in the duodenum. We retrospectively studied the features of pyloric gland adenomas in the duodenum from August 2010 to June 2014. The study group was comprised of 8 patients (5 males and 3 females) with a mean age of 66 years. Mean diameter of the tumor was 12.5 mm. The locations of the tumor were the bulb (n=6) and the second portion (n=2) . The shape of the tumor were type 0-I (n=7) , and 0-IIa (n=1) . Surface structures were villous (n=6) , and convolute (n=2) . We examined 3 cases with magnifying narrow band imaging. White opaque substance (WOS) was observed in the two cases. Microsurface pattern and microvasicular pattern were observed in 2 cases, width and shape of marginal crypt epithelium (MCE) were heterogeneous, and microvasicular pattern showed caliber variation and angiectopia. Endoscopic treatment was performed in 3 cases [EMR (n=2) , and polypectomy (n=1)], and surgery was done in 2 cases [mucosal resection (n=1) , combined resection with advanced stomach cancer (n=1)], and there was no cases with cancerous foci.