A case of adenocarcinoma associated with Peutz-Jeghers syndrome-type gastric polyp treated by endoscopic submucosal dissection

Abstract

An 18-year-old woman was referred to our department for examination of a large gastric polyp. She had one pigmented spot on her upper lip. She did not have a family history of Peutz-Jeghers syndrome. Esophagogastroduodenoscopy revealed a large semipedunculated polyp measuring 50mm in diameter at the greater curvature of the upper gastric body. Pathological examination of a biopsy specimen showed hyperplasia of glandular epithelium and no evidence of malignancy (Group 1) . Endoscopic submucosal dissection (ESD) was performed. Pathological examination of the resected specimen showed smooth muscle bundles with an arborizing appearance throughout the lamina propria with a tiny focus of well-differentiated adenocarcinoma. We reported a case of adenocarcinoma associated with Peutz-Jeghers syndrome-type gastric polyp that was curatively resected by ESD.