A previously healthy, 41 year-old woman was referred to our hospital for further evaluation for a retroperitoneal tumor which was incidentally detected on a CT scan performed at another hospital. The patient was underwent endoscopic ultrasound (EUS) , which revealed 29×24mm low ehogenisity mass, suggestive of arising from gastric wall. The tumor could not rule out gastrointestinal stromal tumor (GIST) , therefore EUS-FNA was attempted with 22 gauge needle via stomach with success. Histrogical specimen did not yield a conclusive diagnosis, therefore, surgical resection was performed. The final histopatological results of surgical specimen showed Castleman’s disease, a hyaline-vascular variant type.
Castleman’s disease of the retroperitoneum is a very rare disease, which has been described that it is difficult to diagnose preoperatively. And there is only a few reports of EUS-FNA for Castleman’s disease. We report a case of retroperitoneal Castleman’s disease which was difficult to diagnosis only by EUS-FNA. This report showed limitation of EUS-FNA for diagnosis for Castleman’s disease, but some possibility of it.