We report the case of a man in his 70s, who was diagnosed with IPMN in the head of the pancreas. The patient was followed-up annually using EUS and magnetic resonance cholangiopancreatography for 12 years. A 9-mm mass in the body of the pancreas was detected via contrast-enhanced computed tomography and EUS. He underwent EUS-FNA, and examination of the biopsy specimen revealed intraductal papillary mucinous carcinoma (IPMC) . He also underwent distal pancreatectomy with splenectomy, and a 5-mm IPMC was confirmed in the surgical specimen.The diagnostic accuracy of EUS-FNA correlates with the tumor size. Although it is useful for the diagnosis of pancreatic cystic tumors, some cases have reported peritoneal dissemination after EUS-FNA. Thus, the usefulness of EUS-FNA for pancreatic cystic tumors remains controversial.