A 53-year-old male visited a clinic nearby for positive fecal blood test and got upper and lower gastrointestinal (GI) endoscopy. The upper one revealed a lesion in stomach and he was introduced to our hospital. A discolored and slightly depressed lesion on the front wall of the gastric antrum was observed by upper GI endoscopy and diagnosed as amyloidosis of AL type by histological examinations of the biopsy samples. Most cases of AL amyloidosis are secondary and systemic and systemic examinations were performed. No lesion except for the stomach was pointed out and the patient was diagnosed as localized gastric amyloidosis. The prognosis of localized amyloidosis in stomach is much better than systemic one and the treatments are quite different, so that a systemic search for amyloidosis is very important when amyloidosis is proved by stomach biopsy.
