Progress of Digestive Endoscopy
Online ISSN : 2187-4999
Print ISSN : 1348-9844
ISSN-L : 1348-9844
Case report
Transformation of MALT lymphoma of rectosigmoid colon to diffuse large B-cell lymphoma: a case report
Masao KusanoMasaki TosaTomoyuki IkedaSeiichi TakahashiShinichi Ikeya
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2021 Volume 98 Issue 1 Pages 118-120

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Abstract

A 60-year-old man, who visited our hospital for further examination of atrophic gastritis on gastric roentgenography and positive of fecal occult blood test on physical examination. Esophagogastroduodenoscopy revealed open-type atrophic gastritis and Helicobacter pylori was positive on urea breath test. Therefore, eradication therapy was performed and successfully eradicated for H.pylori infection. Colonoscopy revealed a submucosal tumor-like elevated lesion in the rectosigmoid colon. The histopathological findings showed chronic inflammation with severe lymphocyte infiltration. After three years and one month, the histopathological findings revealed mucosa-associated lymphoid tissue lymphoma; however, accumulation rate was higher than that on the previous fluorodeoxyglucose-positron emission tomography; hence, we recommended surgery. Laparoscopic partial rectosigmoidectomy was performed, and the diagnosis was diffuse large B-cell lymphoma with lymph node metastasis. Hence, chemotherapy with 3 courses of rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone, was administered. The patient is being followed up.

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© 2021 Japan Gastroenterological Endoscopy Society Kanto Chapter
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