A case of cecal granular cell tumor resected by endoscopic submucosal dissection (ESD)

Abstract

A 60-year-old woman underwent lower gastrointestinal endoscopy and a yellowish submucosal tumor of 5 mm in size was found on the contralateral side of the ileocecal valve. The tumor was diagnosed as a granular cell tumor by endoscopic ultrasonography (EUS) and biopsy examination. ESD was carefully conducted after injection of glycerol. On pathological examination, a tumor consisting of round cells filled with eosinophilic granular spores was found in the submucosa. The spores were strongly positive for S100 protein.

To our knowledge, this is the first report to describe successful treatment of a cecal granular cell tumor by ESD.