1993 Volume 42 Pages 206-208
The patient was a 72-year-old male. Because of an abnormality in the stomach suggested by health examination, he visited our hospital for a work-up.
Since a diagnosis of IIa type early gastric cancer of the cardia was made, surgical treatment was recommended, but he refused. For want of overt signs of remote metastasis, this case was considered an indication for laser therapy. After 6 years of irradiation, the tumor did not grow or show any signs of aggravation so that the course was regarded as favorable. Later on therapy was thwarted by senile dementia and other unfavorable conditions so that he was placed on annual endoscopic observation.
Two years after the discontinuation of laser therapy, a giant ulcerative lesion was found in the gastric corpus at a site removed from the cancerous lesion. A biopsy taken suggested T cell type malignant lymphoma. Seeing that there were no signs of systemic lymphoma, the fresh lesion was considered to be of gastric origin.
The patient was a case of malignant lymphoma of gastric origin which developed in the course of observation of the gastric cancer. The cause and effect relationship between two lesions is yet to be clarified, but the possibility is suggested that an extra-oridnary immune reaction to the cancer gave rise to the malignant lymphoma. This case seems intriguing from the etiological standpoint of coexsisting tumors.
