A Case of Adenosquamous Cell Carcinoma at the Site of the Gastrojejunostomy

Abstract

Adenosquamous cell carcinoma of the stomach is uncommon, especially extremely rare in the residual stomach at the site of the gastrojejunostomy. This report dealed with a case of adenosquamous cell carcinoma at the site of gastrojejunostomy that occured 30-years after the operation of distal gastorectomy and gastrojejunostomy (Billroth-II) for gastric cancer.
A 62-year-old man complaining of chest-abdominal pain and tarry stool was admitted to our hospital. Tumor at the site of gastrojejunostomy was found by both of endoscopic and X-ray examinations. Tumor was histologically diagnosed as adenosquamous carcinoma by endoscopic biopsy. Total resection of residual stomach were performed. The diagnosis after operation was advanced adenosquamous carcinoma at the site of the gastrojejunostomy, that was classified as Borrmann 3 type.
This adenosquamous carcinoma was centrally-grown-type and histologically mixed type of moderately differentiated adenocarcinoma (solid and tubular pattern) and squamous carcinoma. Based on histological examination, these component of squamous cell carcinoma was suggested to arise from squamous metaplasia of adenocarcinoma.