1993 Volume 43 Pages 104-107
Four cases with ulcerative colitis were performed one shot intraarterial administration of corticosteroid whose intensive intravenous administration failed previously. For three cases with severe stage it was not effective, and one of them died in spite of emergent colectomy. But in one performed continuous arterial administration for three days, remission has been was maintained for two years. For one case with moderate stage it was quite effective.
The prompt estimation of the intraarterial administration should be decided because the patient condition was critical. For shortning the judgement time of indication for surgical treatment, intraarterial administration should be selected earlier than intravenous one. Clinical symptoms, ie, abdominal pain, frequency of bowel movement, degree of melena, and body temperature were more helpful to decide the effectivity of intraarterial administration than laboratory data or endoscopy.