1993 Volume 43 Pages 238-241
A 31-year-old male admitted in the Department of Hematology of this hospital for the treatment of osteomyelodysplasia since September 1988 had fever and elevated erythema with pain in the back. The diagnosis of Sweet disease was made when skin biopsy showed diffuse neutrophil infiltration from the superficial to deep dermal layers. He was re-admitted from October 1989 due to exacerbation of Sweet disease but was referred to us when massive bloody stools occurred on January 17, 1990.
Multiple punched-out ulcers were discovered in the cecum upon large bowel endoscopy. Biopsy showed non-specific inflamatory findings. Improvement was seen when complete iv alimentation and oral administration of azelastine hydrochloride were conducted. Colonic ulcers similar to Behçet disease associated with Sweet disease are rare. Our case appears to provide valuable information in determining the casual relationship between these two disease.
