A Study of Tissue Oxygen Tension of The Gastric Mucosa by Endoscopy

Abstract

We employ the laser Doppler method in the measurement of gastric mucosal blood flow, but anemia or like conditions render it difficult to evaluate data obtained by this method. To cope with this problem, gastric mucosal oxygen tension and blood flow were directly measured at the same time.
An endoscope was introduced into the stomach of mongrel dogs in Nembutal anesthesia, and gastric mucosal tissue oxygen tension and blood flow were measured before and after the intravenous administration of butylscopolamine bromide, using a biological tissue oxygen tension continuous measuring apparatus (PO₂100, Intermedical) and PeriFlux PF3, respectively.
The measurement of gastric mucosal tissue oxygen tension seems to provide information not only on oxygenation of the local site of measurement but also on blood flow there.