A Rare Case of Multiple Gastric Carcinoids Developed into a Pedunculated Polyp

Abstract

A 65-year-old female was referred to our hospital because of multiple gastric polyps and anemia for further evaluation. No obvious symptoms related carcinoid tumors were complained (such as flushing, wheezing, diarrhea and so on) .
Upper GI series and endoscopic examination demonstrated multiple gastric polyps on the body of the stomach. A pedunculated polyp (Yamada's classification Type IV, 2.7×2.0×1.5 cm in diameter) was observed at the greater curvature of the upper gastric body. Carcinoid tumors were found histopathologically in all of the specimens biopsied from the polyps. Extensive examination had failed to demonstrate metastasis of carcinoid tumors, then the total gastrectomy was followed.
After surgical resection, carcinoid tumors were found in the pedunculated polyp and all of the gastric polyps pathologically, and they were found in the gastric mucosa, muscularis mucosae and submucosal layer of the body of the stomach.
We could have referred only nine reported cases of gastric carcinoid tumors with pedunculated or semi-pedunculated lesions in Japanese literature including our case. Only two cases were reported which carcinoid tumors had grown to a pedunculated polyp.
In summary, we reported here a very rare case of multiple gastric carcinoids developed into a pedunculated polyp.