Progress of Digestive Endoscopy(1972)
Online ISSN : 2189-0021
Print ISSN : 0389-9403
Clinical study
Helicobacter pylori Infection in Cases of after Distal Gastric Resection-The Role of Bile Acid Refluxed into the Stomach-
Takeshi MatsuhisaIzumi KusamaNobutaka Yamada
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1996 Volume 48 Pages 142-143

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Abstract
Helicobacter pylori (H. pylori) infection in cases of after distal gastric resection was studied. We also examined relation among H. pylori and residual superficial gastritis, bile acid refluxed into the stomach.
1) A rate of H. pylori infection in postoperative stomach shows 51.1%, which was lower than that of digestive ulcer, gastric carcinoma and control group. In cases of residual stomach, a concentration of chenodeoxycholic acid (CDCA) and ursodeoxycholic acid (UDCA) refluxed into the stomach were remarkably higher than thoes of digestive ulcer and control group. I considered the rate of H. pylori infection in postoperative stomach is low because of highly concentrated CDCA and UDCA is not adequate for habitation of H. pylori.
2) There were no correlation among pathological inflammation, activity and superficial gastritis in postoperative stomach. Inflammation and activity were frequent in H. pylori positive cases than negative cases.
3) A frequency of H. pylori infection in cases of after distal gastric resection by gastric carcinoma within 5 years was lower than 50.0%. A rate of infection increased 72.7% in patients who were operated over 5 years ago.
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© 1996 Japan Gastroenterological Endoscopy Society Kanto Chapter
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