Abstract
A 83-year-old female was admitted to our hospital because of right hypochondralgia and abdominal tumor. She was received gastrectomy for early gastric cancer at 78 years old.
Abdominal CT scan showed a tumor in the gastric stump invading to the left lobe of the liver and the pancreas. Endoscopic findings showed an irregular protruded tumor with erosion and bleeding from the gastric stump to the duodenum. Biopsy specimen showed B-cell malignant lymphoma, diffuse medium cell type. Bone marrow aspiration revealed invasion of lymphoma cell. She received dimimished chemotherapy, but she died on 6 months.
Ten cases of malignant lymphoma in the gastric stump after gastrectomy were reported in Japan. The mechanism is supposed to be concerned with metaplasia of gastric mucosa by chronic stimulation by reflux duodenal content and bile juice, depression of gastric acid and change of bacterial flora.