A Case of Esophageal Ulcer Caused by Cytomegalovirus associated with AIDS

Abstract

A 34-year-old woman with AIDS admitted to our hospital because of hematemesis. We performed an endoscopic examination. On this examination, the giant esophageal ulcer was a typical punched out type. And histological examination revealed cytomegalic inclusions which was positive by immunohistostaining. This result showed esophageal ulcer was caused by CMV. The ulcer healed with therapy of gancicrovir (5mg/kg/day) and G-CSF (250mg/2days) after 40 days. And no cytomegalic inclusions were observed in biopsy specimen.
This paper reports a case of typical esophageal ulcer due to CMV associated with AIDs. And gancicrovir was effective for this case. The gastrointestinal complication is important to decide her span of life. It is neccesary to know specific endoscopical findings and we must perform quickly diagnosis and therapy.