1999 Volume 55 Issue 2 Pages 44-47
A 61-year-old man who was pointed out icterus in a previously healthy adult was admitted to our hospital. Findings of blood chemistry showed icterus and liver dysfunction, whereas, hepatitis virus antibodies and HIV antibody were all negative. The patient had heart burn on admission and fecal occult blood was positive. Upper G-I endoscopic finding revealed multiple active ulcers on the duodenum. Culture of Helicobacter pylori from the gastric biopsy specimens and 13C-urea breath test were negative. The patient was treated with H2-receptor antagonist for two months at first, but the duodenal ulcer were unchanged. His intractable duodenal ulcers was diagnosed to be induced by cytomegalovirus (CMV) infection because of high titer of CMV-IgM antibody and detection of CMV-DNA from the liver biopsy specimens using PCR. The patient was tried to treat with anti-CMV drug, Ganciclovir 500mg, for two weeks. His heart burn and epigastralgia were reduced and duodenal ulcers were cured to scar immediately.
