1999 Volume 55 Issue 2 Pages 88-89
A 66-year-old woman was admitted to our hospital because of dyspnea. She was undergone the tumorectomy in her left mandibular malignant melanoma five years ago. Her laboratory data indicated anemia and inflammation. Her dyspnea was considered due to bronchitis and was improved by administration of antibiotics. The endoscopic examination showed a blackish elevated lesion with central depression in the anterior wall of bulbus and pathological findings indicated the invasion of malignant melanoma cells. Multiple metastasis in bilateral adrenal grands, liver, small intestine, and brain were finally discovered, and the combination therapy using IFN-β and DAV (DAV-Feron) was performed. The endoscopic examination after three regimens showed decrease of duodenal lesion and clearance of pigmentation. And CT-scan revealed disappearance of liver metastasis and reduction of bilateral adrenal metastasis. We report have a case of multiple melanoma metastasis successfully treated with chemotherapy.
