Abstract
Atrophy and intestinal metaplasia of gastric mucosa in Helicobacter pylori (Hp) non-infected cases were studied comparing with Hp infected cases.
1) Frequency of endoscopic atrophy at the point of lesser curvature of the lower body in Hp non-infected cases was lower than that of Hp infected cases (each 17.6%, 36.5%) . 17.6% was high score and it was beyond our expectation.
2) We got a positive correlation between age and endoscopic mucosal score in Hp non-infected cases as well as infected cases. It was same in age and intestinal metaplasia score.
3) Frequency of glandular atrophy and intestinal metaplasia were higher in Hp infected cases than non-infected cases except intestinal metaplasia of number 2 specimen.
4) We couldn't find a correlation between age and serum pepsinogen (PG) I/II ratio, PGI/II ratio and endoscopic gastric mucosa in Hp non-infected cases. On the other hand, there were negative correlation between age and PGI/II ratio, PGI/II ratio and endoscopic gastric mucosa in Hp positive cases.