Abstract
This case report describes the 26-year course of periodontal treatment for a woman suffering from generalized aggressive periodontitis since age 24, from the bacteriological, immunological, and clinical points of view. During this course, the patient experienced changes in her life stages such as marriage, moving, childbirths and childcare. Given the potential impact of lifestyle changes on the disease status, an attempt was made to detect the changes of the disease condition before clinical symptoms appeared by monitoring the fluctuations of serum IgG antibody titers against periodontopathic bacteria during the active phase of therapy to the phase of supportive periodontal therapy (SPT). We have discussed the pathological changes influenced by the events in each life stage and the consultations provided to support the patient during the phase of SPT. Based on our observations, we propose a method for long-term care of patients with aggressive periodontitis that begins in the late teens/early twenties. This proposal focuses on the control of oral infection based on the serum IgG antibody titers as an indicator of the disease activity caused by the chronic bacterial infection. Nihon Shishubyo Gakkai Kaishi (J Jpn Soc Periodontol) 56(2)：217-226, 2014.
