2018 Volume 60 Issue 4 Pages 173-182
Acess® toothpaste includes formulation ingredients (latania, chamomile, and myrrh) and reportedly improves periodontal disease by exerting gingival convergence and anti-inflammatory effects. Although each of these ingredients has antibacterial effects, the effects of Acess® on the oral bacteria remain unknown. The present study was aimed at examining the effects of brushing teeth with Acess® on periodontal disease and the oral bacterial population.
This was a randomized, open-label, parallel, intergroup trial. Each participant was randomly assigned to receive either Acess® or a control tooth paste formulation. Participants brushed their teeth twice daily, once in the morning and once in the evening, for five minutes per session. We then assessed clinical parameters such as gingival index (GI), pocket depth (PD), bleeding on probing (BOP) and plaque control record (PCR), and carried out salivary bacteriological examination at baseline and at two and four weeks post-baseline.
In the Acess® group, we observed significant improvement over baseline levels of GI, BOP and PD at two and four weeks. The control group exhibited no significant improvement in any of the clinical parameters. In addition, the Acess® group showed a significant reduction in the total bacterial count as compared with that in the control formulation group. Specific bacteria that were significantly reduced in the Acess® group were Tannerella forsythia, Treponema denticola, and Prevotella intermedia. Furthermore, the rate of bacterial reduction in the Acess® group was significantly improved for the total bacteria, the Red complex, and 5 other strains in the Acess® group.
Acess® significantly reduced the expression of the oral bacteria, including periodontal pathogens, and produced significant improvements in the clinical parameters.
