Second Department of Physiology, Showa University School of Medicine Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
Michiko Iwase
Second Department of Physiology, Showa University School of Medicine
Masahiko Izumizaki
Second Department of Physiology, Showa University School of Medicine
Mitsuko Kanamaru
Second Department of Physiology, Showa University School of Medicine
Ikuo Homma
Second Department of Physiology, Showa University School of Medicine
We tested the hypothesis that the biphasic ventilatory response to poikilocapnic hypoxia shows circadian variation and contribution of histamine H1 receptors in mice. Initial increases in ventilation were augmented during dark periods. H1 receptors had no major relationship with circadian variation, but affected the declined phase.
