抄録
The first demonstration of how biochemical changes in neurons in specific parts of the brain direct a complete mammalian behavior derived from the effects of estrogens in hypothalamic neurons that facilitate lordosis behavior, the primary reproductive behavior of female quadrupeds (Pfaff, 1980, 1999). Sex behaviors depend on sexual arousal that depends in turn on a primitive function: generalized CNS arousal (Pfaff, 2006). Here we summarize one of the ways in which a generalized arousal transmitter, norepinephrine, can influence the electrical excitability of ventromedial hypothalamic cells in such a way as to foster female sex behavior.