Proceedings of the Japan Academy
Print ISSN : 0021-4280
Cellular Basis of Immunity. III
Cross Immunity of the Mouse Mononuclear Phagocytes Immunized with Live Vaccine of Salmonella enteritidis against S. typhimurium, S. choleraesuis, E. coli, and Mycobaterium tuberculosis
Ichiei SATOTokumitsu TANAKAKazuko SAITOSusumu MITSUHASHI
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1962 Volume 38 Issue 3 Pages 133-138

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Abstract

According to the present investigation in the course of infection of the mice with facultative cytotrophic bacteria the following results were obtained.
Infection in vitro with S. enteritidis, S. typhimurium, S. choleraesuis, E. coli and M. tuberculosis H37Rv of mononuclear phagocytes derived from the abdominal cavity of the mice showed that the intracellular multiplication of these strains was rapid, and phagocytes were destroyed after 3-5 days of incubation.
Cells obtained from the mice immunized with live vaccine of S. enteritidis inhibited intracellular growth of S. typhimurium, S. choleraesuis, S. enteritidis, and E. coli 0-55, regardless of the presence of immune sera.
But the cells of normal as well as immunized mice with live or dead vaccine of S. enteritidis did not inhibit the intracellular multiplication of M. tuberculosis H37Rv.

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