According to the present investigation in the course of infection of the mice with facultative cytotrophic bacteria the following results were obtained.
Infection
in vitro with
S. enteritidis, S. typhimurium, S. choleraesuis,
E. coli and
M. tuberculosis H37Rv of mononuclear phagocytes derived from the abdominal cavity of the mice showed that the intracellular multiplication of these strains was rapid, and phagocytes were destroyed after 3-5 days of incubation.
Cells obtained from the mice immunized with live vaccine of
S.
enteritidis inhibited intracellular growth of
S. typhimurium, S.
choleraesuis, S. enteritidis, and
E. coli 0-55, regardless of the presence of immune sera.
But the cells of normal as well as immunized mice with live or dead vaccine of
S. enteritidis did not inhibit the intracellular multiplication of
M. tuberculosis H37Rv.
View full abstract