Treatment of Experimental Atherosclerosis by Pyridinolcarbamate
A Preliminary Report
1965 年 41 巻 8 号 p. 751-756
詳細
1965 年 41 巻 8 号 p. 751-756
Pyridinolcarbamate, a bradykinin-antagonist showed no hypocholesterolemic effect, but, exhibited definitely a curative effect in atheroma of cholesterol-fed rabbits. The appearance of its curative effect was prompt and the leading repair process was the replacement of atheromatous mass with regenerated smooth muscle fibres which begins early within the first week of the treatment and progresses gradually in the course of over 15 weeks even under the high serum cholesterol level.
