Proceedings of the Japan Academy, Series B
Online ISSN : 1349-2896
Print ISSN : 0386-2208
ISSN-L : 0386-2208
Cytogenetical Study on the New Myeloproliferative Disorder, L-8313, found in the Irradiated Mouse
Isamu HAYATAKazuko YOSHIDATomohiko ICHIKAWAYayoi HIRANOMasatoshi SEKI
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1987 Volume 63 Issue 1 Pages 13-16

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Abstract
A transplantable myeloproliferative disorder, L-8313, is found in the irradiated C3H/He male mouse. The chromosome analysis reveals that dominantly proliferating cells in the mouse with L-8313 are normal cells. The involvement of virus in the passage is denied by virus detection tests. It is suggested that L-8313 is a new myeloproliferative disorder where most of the increased cells are normal cells stimulated by the malignant T cells.
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