Identification of genes in the complete genomic DNA sequence of a hyper-thermophilic archaeon, Pyrococcus sp. OT3

Abstract

By using the algorithm for identifying transcription units-i.e. independently regulated ORFs and operons, and pseudo-genes, that was described in our earlier paper (Suckow et al., FEBS Letters, in press), the 1, 738, 505 base sequence that covers the whole genome of Pyrococcus sp. OT3 has been analyzed. ORFs of the number, 1, 819, and 51 RNA genes have been identified. For 42% of the identified ORFs significant homology has been found to the known protein genes of known function, and thus these were identified as protein genes, while for 31% homology has been found to the known ORFs of unknown function. For the rest 27% no significant homology has been found.