Histopathological Study on Minute Cancers Associated with the Autrum Gastritis.

Abstract

The well differentiated early gastric cancer was conclusively originated from antral gastritis with minute cancers with the diameter of less than 5 mm. For the present study, 92 cases of well differentiated early gastric cancers including minute cancers, 110 cases of various benign gastric diseases (30 cases of duodenal ulcer, 30 cases of gastric hyperplastic polyp, and 50 cases of gastric ulcer), 25 cases of control, and 8 cases of gastric atypical epithelium (A.T.P.) were studied histopathologically in relation to their antral gastritis. The histological study revealed the protruded type (Type I) of early gastric cancer closely related with the gastric hyperplastic polyp, and the elevated type (Type II a or II a + II c) also closely related with A.T.P Many depressed or excavated types (Type II c, II c+ III or III) with shallow ulcers (U1-II) would be originated from the secondary ulcer in depressed type without ulcers. Many depressed or excavated types with deep ulcers (U1-III or U1-IV) wocld be originated from deep benign gastric ulcers (U1-III or U1-IV). It was concluded that a close relationship was present between well differentiated type of early gastric cancer and intestinal metaplasia.