Juntendo Medical Journal
Online ISSN : 2188-2134
Print ISSN : 0022-6769
ISSN-L : 0022-6769
Clinical and Histo-Pathological Studies on Congenital Biliary Atresia
Part 1. Liver cell change and prognosis
YASUNORI KOJIMA
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1981 Volume 27 Issue 3 Pages 305-315

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Abstract
The histo-pathological studies on 84 resected livers taken at the radical operations of congenital biliary atresia were concluded that conditions of liver cell were devided into 3 groups (Cn-classification) according to nuclei number of liver cells in (130μ) 2; i.e. C1 : _??_37 (40 cases), C2 : 38_??__??_48 (37 cases), C3 : 49_??_ (7 cases). Nine autopsy infantile cases and 5 cases of resected livers were studied as the control groups. Most cases of the C1 and C2 groups showed slight (F1) to moderate (F2) liver fibrosis. Most cases of C1 and C2 groups showed more than 100μ inside diameter of hepatic bile duct at porta-hepatis. Most cases of C1 or C3 group showed younger or older operative age, respectively. Clinicall, 22 out of 25 cases (88%) of C1 and C2a (the subtype in C2 group) groups showed good prognosis. Most cases (85.7%) of C3 group showed worse prognosis.
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© 1981 The Juntendo Medical Society
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