Abstract
The endocrine features of 28 patients with hyperprolactinemia and outcome after treatment were studied. The patients were divided into following three groups, according to the causes of hyperprolactinemia: the pituitary tumor, the drug-induced, and the unknown cause groups, the majority of patients being the drug-induced group of 12 cases. In the pituitary tumor group, serum prolactin levels were higher than in the other groups, and serum FSH levels were significantly lower than those in the control group. Poor prolactin response to TRH was found in both the pituitary tumor and unknown cause groups. Pituitary function of the patients with hyperprolactinemia was observed to be well maintained regardless of the cause of the condition. In a follow-up study, full ovarian response was found in 14 of the 28 patients.
