Juntendo Medical Journal
Online ISSN : 2188-2134
Print ISSN : 0022-6769
ISSN-L : 0022-6769
Experimental Studies on Arsenic Poisoning
Report 2. On the Histological Findings by Giving Arsenious Acid into the Stomach of Mice
Kazuteru NITTA
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1958 Volume 4 Issue 1 Pages 47-51

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Abstract
The present paper deals with a part of the series of the author's studies on experimental arsenious poisoning. Expriments were made by giving 1% arsenious acid solution into the stomach of mice, inbred strain ddY. After mice were killed by ether, their specimens were stained by Hematoxylin and partly Sudan III. For histochemical studies, Schümacher's method was used. The following results were obtained. (1) Histological changes by arsenious acid were most severely in the kidneys and nextly in the liver. Marked atrophy was seen in the spleen. (2) Arsenic granules were detected more frequently in the liver and the spleen than in other organs. (3) Presence of the arsenic granules were not seemed to have any relation to disturbance of the organ.
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© 1958 The Juntendo Medical Society
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