Abstract
We report two cases of human parvovirus-B19 infection mimicking systemic lupus erythematosus. Both patients presented with rash, fever, arthritis, cytopenia, hypocomplementemia and positive antinuclear antibodies. These initial manifestrations strongly suggested a diagnosis of systemic lupus erythematosus. However, serologic studies indicated recent human parvovirus-B19 infection. Regression occurred clinically and serologically within one year. It is considered that human parvovirus-B19 infection manifests lupus-like presentation and accompanies a transient autoimmune state.
