Abstract
COPD is a disease state characterized by progressive airflow limitation that is not reversible and by an abnormal inflammatory response of the lungs to noxious particles and gases. There is also a growing realization that COPD is a multi-organ-system disease. To reduce symptoms, improve QOL, and increase physical and emotional participation in everyday activities, comprehensive management including pharmacologic treatment, pulmonary rehabilitation, and oxygen therapy is mandatory. COPD is currently the fourth leading cause of death in the world. To reverse further increase in its prevalence and mortality in the coming decades, continuous improvements in management and prevention strategies are necessary.
