Abstract
Although the mortality rate of the breast cancer is decreasing in western countries, the incidence is increasing all over the world. The development of safe and effective treatment and early detection of the cancer are required first, even if the carcinogenesis of breast cancer should be discovered theoretically, since methods of disrupting the developmental process have yet to be resolved.
Currently, the standard therapy for breast cancer is minimally required local therapy and maximal systemic therapy. The prognosis is influenced by the extent of disease at diagnosis, I. e. whether it is already a systemic disease or not and the response of each cancer to chemotherapy. The purpose, regimen and evidence for various kinds of chemotherapy : primary systemic chemotherapy (PSC), adjuvant chemotherapy and chemotherapy for metastasis are described in this paper.
