Abstract
Autophagy is a catabolic process involved in cellular events including development, aging, immunity and cell death. It is evolutionarily conserved and ubiquitous among eukaryotic cells. In higher eukaryotes, autophagic dysfunction has been associated with cancer, certain muscular diseases and neurodegeneration. Autophagic pathways differ in the way that cytosolic components and organelles are delivered to the lysosome or vacuole. In recent years, morphological, genetic, biochemical and cell biological approaches have begun to provide insight into the molecular mechanisms underlying autophagy. I received on opportunity to study cell biology, especially autophagy, with Prof. Junying Yuan in Harvard Medical School. This time, I would like to outline the recent autophagy progress and show my current data in autophagy.
