The first case of cadaveric donor liver transplantation in Juntendo University Hospital

Abstract

Living donor liver transplantation (LT) has been recognized as an effective therapeutic method for end-stage liver disease in Japan. However, cadaveric donor LT has been rarely performed, even after the establishment of the organ-transplant law in 1997. With an amendment of organ-transplant law in July 2010, another 8 institutions, including Juntendo University Hospital, obtained national authorization for cadaveric donor LT. We herein describe the first case of cadaveric donor LT in Juntendo University Hospital. The recipient was a 53-year-old man with fulminant hepatitis. In December 2010, he was registered as a candidate for cadaveric donor LT after evaluation by both Juntendo University and national committees. After 4 days from registration, he underwent cadaveric donor LT and received a whole graft obtained from a cadaveric donor. Although invasive aspergillus infection was developed postoperatively, his condition was improved by administration of liposomal amphotericin B and voriconazole. The patient was discharged 97 days after transplantation.