Abstract
The present paper deals with the part of the series of the author's studies on experimental poisoning of benzol groups.
Experiments were made by giving 0.4cc/kg of nitrobenzol into the stomach of mice, inbreed strain ddN.
Authors studied on concentrations of erythorocytes, leucocytes, hemoglobin and blood pictures of mice. After mice were killed by luxation of spinal vertebrae, their histopathological specimens were stained by Haematoxylin and partly Sudan III.
The following results were obtaned. :
1. Body weight decreaeed soon after the administration, but then showed the increasing tendency.
2. All mice showed cyanosis after giving nitrobenzol.
3. On the hematological findings :
a) Concentration of leucocytes decreased remarkably, and the recovered gradually.
b) Concentration of erythrocytes slightly decreased.
c) Hemoglobin also decreased, but this tendency was kept pace with the mode of erythrocytes.
d) On blood pictures, neutrophilic leucocytes remarkably increased, while lymphocytes decreased relatively.
4. On histopathological findings :
Little differences were found among the changes of various organs and most remarkable disturbaces were observed in the liver, kidney, spleen, lungs and gastrointestinal tracts.
