抄録
Out of the non-estrogenic acid fraction of pregnant mare urine a christalline component (provisio-nally called synstrone C) was isolated by means of adsorbtion to activated carbon, elution by phenol and chromatography. This substance did not show estrogenic activity by itself, but it augmented estrogenic hormone in some degree, if given simultaneously to spayed mature female mice. On the other hand the same substance brought similar reaction to that of progesterone in uterine stromal nuclei of spayed mice according to the progestin test of Hooker-Forbes.
The substande synstrone C included nitrogen in 17% and displayed a characteristic fluolescence if concentrated sulfuric acid was added.
