Juntendo Medical Journal
Online ISSN : 2188-2134
Print ISSN : 0022-6769
ISSN-L : 0022-6769
The Effect of Saline and Sucrose-Phosphate-glutamate Solution on the Experimental Infection with Rickettsia Orientalis in Mice
The Difference in the Appearance of Rickettsia in the Blood of Mice Inoculated Intraperitoneally
Takahiro SUGAWARAShigeru ISHIHARATatsuya IIJIMA
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1960 Volume 6 Issue Supplement Pages 635-637

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Abstract
Two sorts of solution, saline and Sucuose-Phosphate-Glutamate solution (Bovarnick), were used in preparing emulsion of the spleens, which were obtained from mice infected with Rickettsia orieAtalis. Each emulsion was injected intraperitoneally to the two groins of normal mice respectively. The mice were bled by severing the femoual vessels at intervals after inlection. Blood was collected and diluted 10-fold series with SPG-solution. 0.3ml of each dilution was inlected intuapeuitoneally to groups of 5 normal mice. The rate of fatal outcome with rickettsial infection was greater in the guoup injected SPG-emulsion than saline emulsion. This results indicate that in the case of SPG-eunulsion the absouption of Rickettsia from abdominal cavity of mice is faster and more intensive than in that of saline-emulsion.
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© 1960 The Juntendo Medical Society
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