Juntendo Medical Journal
Online ISSN : 2188-2134
Print ISSN : 0022-6769
ISSN-L : 0022-6769
Influence of Pituitary-Adrenocortical Hormones on the Phagocytic Action of Leucocytes.
Yutaka SHIBANUMA
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1961 Volume 7 Issue Supplement1 Pages 652-660

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Abstract
These experiments were studied principally the influence of pituitary-adrenocortical hormone (ACTH, cortisone etc) on the phagocytic action of leucocytes of rabbits which were secondary adrenalectomized before and after. 1) In the directly mixed examination in vitro, the phagocytic action was remarkably decreased by Dexamethason, and was not at least decreased by ACTH and cortisone. 2) In the normal rabbits which, was administrated ACTH and cortisone, the phagocytic action in 24 hours was increased after slightly decrease in the beginning and the number of leucocytes remarkably increased. 3) In the unilateral adrenalectomized rabbits which was administrated both ACTH and cortisone increasing number of leucocytes was decreased and decreasing phagocytic aotion was increased. In the bilaterale adrenalectomized, the number of leucocytes was increased and the phagocytic action did not almost influence. It is suggested by the above observation, the influence of the phagocytosis by pituitaryadrenocortical hormone in rabbit is not due to through the suprarenal body but general condition by their subsistence or not.
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© 1961 The Juntendo Medical Society
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