False Positive Reduction Using Vascular Structure and Location Information for Cerebral Aneurysm Detection Model on MR Angiography

Abstract

Rupture of a cerebral aneurysm is a major cause of subarachnoid hemorrhage. Therefore, early detection and medical treatments of aneurysm are crucial. MRA images are widely used to diagnose cerebral aneurysms, and several methods using CNN have been proposed to detect cerebral aneurysms on MRA images automatically. In particular, the method using Multi-Modal CNN, which combines 3DMRA and 2D images through MIP (Maximum Intensity Projection) method, can achieve high sensitivity. However, this method does not utilize the location and geometrical information of lesion candidates in the brain, resulting in many false detections as a drawback. In this study, after reducing the number of false positives by using the location and vascular structure of lesion candidates in preprocessing steps, we put them into Multi-Modal CNN as inputs. As experiments result, we achieved a lower false detection rate with the same detection sensitivity when compared to the previous research.