Brain Reference Architecture Integration of Hippocampal Formation and Amygdala

Towards a Functional Hypothesis Construction for Emotion-Adaptive Navigation

Abstract

In brain reference architecture (BRA)-driven development, architectures have been constructed for brain regions with relatively clear functions, such as the hippocampus and amygdala. The hippocampus plays a crucial role in spatial cognition and episodic memory, while the amygdala is essential for adaptive fear conditioning. In this paper, we survey the anatomical structures that connect the two brain regions by integrating the two BRAs of the hippocampus and the amygdala, which are adjacent brain regions. We also consider how the interaction between the two brain regions relates to the functions of spatial cognition and fear conditioning, providing insights into constructing a functional hypothesis.